Macromolecular Crystallization Facility (UCLA)

Consultation and technical assistance available to researchers prior to, and following, experiments. Evaluation of sample via Dynamic Light Scattering. Automatic setup of 4000 crystallization conditions per hour using 500uL of sample. (Hanging or Sitting Drops). The Mosquito from TTP, Labcyte ECHO525 and Tecan GENESIS are used for Liquid Dispensing.  Capable of distinguishing between organic and inorganic crystals using a sophisticated UV/vis microscope. Optimization of crystallization conditions. Storage of plates in temperature controlled incubators at 4, 15, and 20C. Optimization of crystallization conditions using a library of 1,500 commercial compounds. Affinity and Kinetics Characterization with the ForteBio OCTET Red96 instrument. The Labcyte ECHO 525 is used for acoustic liquid dispensing. Production of stereolithography files from Pymol, 3D design of labware, 3D SLA and Filament printing.

For more information, please visit the Macromolecular Crystallization Facility site.

Last updated
September 27, 2023