Informatics for Integrating Biology & the Bedside

Harvard’s i2b2 (Informatics for Integrating Biology and the Bedside) Center produces an open source data warehouse software system that enables clinical researchers to use existing clinical data for discovery research. The i2b2 platform currently enjoys wide international adoption by the CTSA network, academic health centers, and industry. Within the UCLA CTSI, the i2b2 data warehouse system forms the cornerstone for research access to clinical data across the CTSI. All four CTSI partner institutions are using i2b2 or are currently in the process of implementing it. UCLA has implemented it atop xDR; Cedars populates it directly from its Epic EHR; Harbor, through its parent organization, the LA County Department of Health Services (LAC DHS), which implemented it along with their Cerner EHR system; and CDU implemented i2b2 to serve a number of community clinics (Venice Family Clinic, San Fernando Valley Health Center, and the LA Net coalition). 

The i2b2 Cohort Discovery System contains data from 2.5 million unique patients at UCLA. i2b2 is secure and designed for UCLA investigators to conduct searches on clinical data from Ronald Reagan UCLA Medical Center, Santa Monica UCLA Medical Center and other UCLA-affiliated clinics and departments. The search results provide a numeric count of patients that are based on de-identified data extracted from UCLA’s clinical data warehouse. Search criteria include demographics, diagnosis and procedure codes (ICD-9, ICD-10 and CPT), labs, medications, visit details (including site locations), vital signs and vital status.

For more information, please visit the i2b2 webpage. 

Last updated
November 17, 2023